Antitumor effects of cationic synthetic peptides derived from Lys49 phospholipase A2 homologues of snake venoms

Antitumor effects of cationic synthetic peptides derived from Lys49 phospholipase A2 homologues of snake venoms

Source :

• Cell Biology International [ 1065-6995 ] ; 2007-03.

Descripteurs français

• KwdFr :
  • Animaux, Antinéoplasiques (pharmacologie), Cellules cancéreuses en culture, Fragments peptidiques (), Fragments peptidiques (pharmacologie), Fragments peptidiques (synthèse chimique), Group II Phospholipases A2, Injections péritoneales, Membranes (), Mort cellulaire (), Phospholipases A (), Phospholipases A2, Protéines de reptiles, Souris, Souris de lignée BALB C, Séquence d'acides aminés, Tumeurs expérimentales (anatomopathologie), Tumeurs expérimentales (métabolisme), Tumeurs expérimentales (traitement médicamenteux), Tumeurs expérimentales de la mamelle (traitement médicamenteux), Venins de crotalidé ().
• MESH :
  • anatomopathologie : Tumeurs expérimentales.
  • métabolisme : Tumeurs expérimentales.
  • pharmacologie : Antinéoplasiques, Fragments peptidiques.
  • synthèse chimique : Fragments peptidiques.
  • traitement médicamenteux : Tumeurs expérimentales, Tumeurs expérimentales de la mamelle.
  • Animaux, Cellules cancéreuses en culture, Fragments peptidiques, Group II Phospholipases A2, Injections péritoneales, Membranes, Mort cellulaire, Phospholipases A, Phospholipases A2, Protéines de reptiles, Souris, Souris de lignée BALB C, Séquence d'acides aminés, Venins de crotalidé.

English descriptors

• KwdEn :
  • Amino Acid Sequence, Animals, Antineoplastic Agents (pharmacology), Cell Death (drug effects), Crotalid Venoms (chemistry), Group II Phospholipases A2, Injections, Intraperitoneal, Mammary Neoplasms, Experimental (drug therapy), Membranes (drug effects), Mice, Mice, Inbred BALB C, Neoplasms, Experimental (drug therapy), Neoplasms, Experimental (metabolism), Neoplasms, Experimental (pathology), Peptide Fragments (chemical synthesis), Peptide Fragments (chemistry), Peptide Fragments (pharmacology), Phospholipases A (chemistry), Phospholipases A2, Reptilian Proteins, Tumor Cells, Cultured.
• MESH :
  • chemical , chemical synthesis : Peptide Fragments.
  • chemical , chemistry : Crotalid Venoms, Peptide Fragments, Phospholipases A.
  • chemical , pharmacology : Antineoplastic Agents, Peptide Fragments.
  • drug effects : Cell Death, Membranes.
  • drug therapy : Mammary Neoplasms, Experimental, Neoplasms, Experimental.
  • metabolism : Neoplasms, Experimental.
  • pathology : Neoplasms, Experimental.
• Teeft :
  • Amino Acid Sequence, Animals, Antimicrobial, Antimicrobial activity, Antimicrobial peptides, Antitumor, Antitumor activity, Antitumor effect, Antitumor effects, Asper, Bactericidal activity, Biol chem, Body weight, Bothrops, Bothrops asper, Bothrops asper snake venom, Carcinoma cells, Cationic, Cationic peptides, Cell biology, Cell line control, Cell lines, Comparative study, Costa rica, Crotalid snake venoms, Cytolytic, Cytolytic activity, Cytolytic effect, Emt6, Endothelial cells, Fetal calf serum, Group II Phospholipases A2, High concentrations, Homologues, Injections, Intraperitoneal, Innate immunity, International federation, Intraperitoneal route, Lactate dehydrogenase, Latter case, Lomonte, Lomonte cell biology, Lytic action, Mice, Mice, Inbred BALB C, Murine, Murine tumor cell lines, Myotoxic, Myotoxic phospholipases, Myotoxin, Normal cells, Papo, Peptide, Phospholipase, Phospholipases A2, Piscivorus, Pla2, Pla2 homologues, Present work, Proc natl acad, Reptilian Proteins, Similar magnitude, Skeletal muscle, Skeletal muscle myoblasts, Snake venom, Snake venoms, Synthetic peptides, Toxicon, Toxicon lomonte, Toxin, Tumor Cells, Cultured, Tumor cell lines, Tumor cells, Tumor growth, Tumor mass reduction, Tumor masses, Venom.

Abstract

• https://api.istex.fr/ark:/67375/WNG-DVT2V7BG-R/fulltext.pdf

Affiliations:

• Costa Rica

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